NCT04958031
A Trial of the Safety, Tolerability, and Pharmacodynamics of CVL-871 in Subjects With Dementia-Related Apathy
Brief summary
The purpose of this study is to determine whether CVL-871 is safe and tolerable in patients with Dementia-Related Apathy and if CVL-871 shows changes in clinical measurements of apathy.
Interventional study
Status:
Completed
Conditions:
Apathy in Dementia
Enrollment:
41 patients
Phase:
- 1
- 2
- 3
- 4
Protocol ID:
CVL-871-2001
Allocation:
Randomized
Intervention model:
Parallel Assignment
Masking:
Triple (Participant, Care Provider, Investigator)
Purpose:
Treatment
Participant attributes:
Male and Female
Age:
From 50 Years to 85 Years.
Inclusion Criteria:
- Meets diagnostic criteria for apathy in neurocognitive disorders
- Clinically significant apathy
- Mild to Moderate Dementia (AD, FTD, VAD, or DLB)
Exclusion Criteria:
- Other significant psychiatric disorder(s)
- Other neurological disorders (other than AD, FTD, VAD, or DLB)
